First preimplantation genetic diagnosis of hereditary retinoblastoma using informative microsatellite markers
نویسندگان
چکیده
منابع مشابه
First preimplantation genetic diagnosis of hereditary retinoblastoma using informative microsatellite markers.
Retinoblastoma is a malignant intra-ocular tumour of developing retina initiated by inactivation of both alleles of the retinoblastoma susceptibility (RB1) gene. This paper reports the first clinical experience of preimplantation genetic diagnosis (PGD) for hereditary retinoblastoma using two highly polymorphic microsatellite markers RB1.20 and D13S284, located within and close to the RB1 gene ...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2003
ISSN: 1460-2407
DOI: 10.1093/molehr/gag014